博奥森.bs-1278R 8-OHdG/DNA/RNA Damage8-羟基脱氧鸟苷/DNA/RNA Damage抗体 100ul Bioss


货品编号: 博奥森.bs-1278R 品牌:博奥森 品名:8-OHdG/DNA/RNA Damage8-羟基脱氧鸟苷/DNA/RNA Damage抗体 规格:100ul 产品描述:

background: 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are

formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence

to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases

in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis,

inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.

Function: Oxoguanine 8 (8-Oxoguanine) is a mutagenic oxidative damage product of guanine. Guanine is the main target for reactive

oxygen species in DNA, with 8-oxoguanine being the most frequent base lesion. Thus formation of 8-oxoguanine is an

important biomarker of oxidative damage to DNA. It is primarily repaired by the DNA glycosylase OGG1.

© 金山科研平台 Thermo Fisher官网Nunc、QSP、Nalgene、Invitrogen、Gibco耗材试剂授权一级代理是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://thermonunc.cn/thread-4639.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价