货品编号： 博奥森.bs-7654R 品牌： 博奥森 品名：TIP30 TIP30蛋白抗体 规格： 100ul 产品描述：

background: Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear

import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription

through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic

properties. Isoform 2 has an antiapoptotic effect. Tissue specificity: Ubiquitous. Highest level in liver. High levels in lung, skeletal muscle, pancreas and placenta. Moderate

levels in heart and kidney. Low levels in brain.

Function: Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear

import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription

through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic

properties. Isoform 2 has an antiapoptotic effect.