博奥森.bs-1859R NGB脑红蛋白/神经血红蛋白/神经球蛋白抗体 50ul Bioss


货品编号: 博奥森.bs-1859R 品牌:博奥森 品名:NGB脑红蛋白/神经血红蛋白/神经球蛋白抗体 规格:50ul 产品描述:

background: This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly

conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be

involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions. [provided by

RefSeq, Jul 2008]

Function: Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal

His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase

activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative

stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release

necessary to commit the cells to apoptosis.

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