货品编号: 博奥森.bs-1859R 品牌:博奥森 品名:NGB脑红蛋白/神经血红蛋白/神经球蛋白抗体 规格:50ul 产品描述:
background: This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly
conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be
involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions. [provided by
RefSeq, Jul 2008]
Function: Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal
His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase
activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative
stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release
necessary to commit the cells to apoptosis.
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