货品编号： 博奥森.bs-0630R 品牌：博奥森 品名：Angiotensin II Type 1 Receptor血管紧张素Ⅱ-1型受体抗体 规格：50ul 产品描述：

background: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector

controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This

gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene

may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted

myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that

there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene.

Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is

contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].

Function: Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium

second messenger system.