货品编号： Bioss.bs-23103R 品牌：Bioss 品名：Rabbit anti KI 67 antibody 规格：100ul 产品描述：

background: Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases

of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful

in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the

number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the

prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67

index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling

and proliferation.

Function: Thought to be required for maintaining cell proliferation.

Subcellular Location: Nucleus. Chromosome. Predominantly localized in the G1 phase in the perinucleolar region, in the later phases

it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis,

it is present on all chromosomes.