货品编号： Thermo.12-0114-81 品牌：Thermo 品名：Anti-Mouse CD11c PE 规格：50ug

产品描述： Product Specific Information Description: The N418 monoclonal antibody reacts with mouse CD11c, the integrin alphaX. CD11c non-covalently

associates with beta2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset

of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and

fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the

T-dependent areas of mouse spleen and precipitates a 150, 90 kDa heterodimer.

Applications Reported: The N418 antibody has been reported for use in flow cytometric analysis.

Applications Tested: The N418 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can

be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell

sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8

cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.

Filtration: 0.2 µm post-manufacturing filtered.