货品编号: bioss.bs-10009R 品牌:bioss 品名:上皮钙粘附分子抗体 规格:20ul
产品描述: background: Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance
of tissue structure and morphogenesis. Members of this family of adhesion proteins include rat cadherin K (and its human homolog,
cadherin-6), R-cadherin, B-cadherin, E/P cadherin and cadherin-5. The classical cadherins, E-, N- and P-cadherin, consist of large
extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to
be responsible for binding specificity, transmembrane domains and carboxy terminal intracellular domains. The relatively short intracellular
domains interact with a variety of cytoplasmic proteins, such as ∫-catenin, to regulate cadherin function.
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