Jackson.709-006-073 AffiniPure F(ab')₂ Fragment Donkey Anti-Human IgM, Fc5μ fragment specific 1.0 mgJackson


货品编号: Jackson.709-006-073 品牌:Jackson 品名:AffiniPure F(ab')₂ Fragment Donkey Anti-Human IgM, Fc5μ fragment specific 规格: 1.0 mg

产品描述:

F(ab')2 fragment antibodies are generated by pepsin digestion of whole IgG antibodies to remove most of the Fc region while

leaving some of the hinge region. F(ab')2 fragments have two antigen-binding Fab portions linked together by disulfide bonds

and therefore they are divalent. The average molecular weight is about 110 kDa. They are used for specific applications, such

as to avoid binding of secondary antibodies to live cells with Fc receptors or to Protein A or Protein G.

Based on immunoelectrophoresis and/or ELISA, the antibody reacts with the Fc5µ portion of the human IgM heavy chain but

not with human IgG, IgA, or the light chains of human immunoglobulins. No antibody was detected against non-immunoglobulin

serum proteins. The antibody has been tested by ELISA and/or solid-phase adsorbed to ensure minimal cross-reaction with bovine

and horse serum proteins, but it may cross-react with IgM from other species.

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