货品编号： biolegend.302913 品牌：biolegend 品名：LEAF™ Purified anti-human CD28 规格：50ug

产品描述：

Description CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin

superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and

plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28

is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing

cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells

provides a costimulatory signal required for T cell activation and proliferation.