货品编号： biolegend.589102 品牌：biolegend 品名：Recombinant Human IL-2 (carrier-free) 规格：10ug
产品描述：
Description
IL-2 was discovered through its function as a T cell growth factor (TCGF), and plays a pivotal role in immune
responses against pathogenic infection. Recognition and binding of the foreign Ags by the TCRs stimulate both
the secretion of IL-2 and the expression of IL-2Rs on the T cell surface. Subsequently, the IL-2/IL-2R interaction
activates the intracellular Ras/Raf/MAPK, JAK/STAT, and PI3K/AKT signal pathways, and ultimately stimulates
the growth, differentiation, and survival of the Ag-selected cytotoxic T cells. Human IL-2 acts on murine and human
T cells, and its receptors are shared by others cytokines. IL-2Rα is an IL-2–specific receptor, IL-2Rβ is shared with
IL-15 and the γ chain that is a common receptor shared by many cytokines including IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21.
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