货品编号: 博奥森.bs-0380R 品牌:博奥森 品名:髓鞘碱性蛋白/磷脂碱性蛋白抗体 规格:50ul 储存条件:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature
for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS
or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品描述:
background: The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein
components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller
isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of
MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before
myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells
and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of
isomers, each of them having maybe a specialized function.
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