货品编号： 博奥森.bs-1447R 品牌：博奥森 品名：缺氧诱导因子2α /HIF-2α/HIF-2-alpha抗体 规格：50ul 储存条件：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for

at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or

diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

产品描述：

background: Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within

the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF)

expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a

role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase

expression. Activation requires recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction

with redox regulatory protein APEX seems to activate CTAD.