货品编号： Biolegend.123108 品牌：Biolegend 品名：FITC anti-mouse F4/80 规格：500 ug

产品描述： F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane

7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which

is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut,

thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and

Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset

of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required

for induction of CD8+ T cells-mediated peripheral tolerance.