产品描述： background: Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of

non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates

IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of

NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes.

Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free

DNA repair pathway and contributes to the survival of cells after DNA damage.