货品编号： 博奥森.bs-7882R 品牌：博奥森 品名：泛素结合酶E2变异体1抗体 规格：100ul
产品描述： background: Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of
non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates
IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of
NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes.
Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free
DNA repair pathway and contributes to the survival of cells after DNA damage.
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