博奥森.bs-9862R 肌球蛋白重链7抗体 50ul Bioss


货品编号: 博奥森.bs-9862R 品牌:博奥森 品名:肌球蛋白重链7抗体 规格:50ul

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background: Myosin heavy chains are ubiquitous Actin-based motor proteins that convert the chemical energy derived from ATP

hydrolysis into the mechanical energy that drives diverse motile processes in eukaryotic cells, including cytokinesis,

vesicular transport and cellular locomotion. Muscle myosin is a heterohexamer consisting of two myosin heavy chains

and two associated nonidentical pairs of myosin light chains. The seven myosin heavy chain isoforms that predominate

in mammalian skeletal muscles include two developmental isoforms, MHC-embryonic (MYH3) and MHC-perinatal (MYH8);

three adult skeletal muscle isoforms, MHC IIa (MYH2), MHC IIb (MYH4) and MHC IIx/d (MYH1); and MHC-∫/slow (MYH7

or MHC-∫), which is also expressed in cardiac muscle. Research indicates that mutations of the MYH7 gene causes

hypertrophic cardiomyopathy.

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