博奥森.bs-2527R CD163抗体 50ul Bioss


货品编号: 博奥森.bs-2527R 品牌:博奥森 品名:CD163抗体 规格:50ul

产品描述: background: CD163 is a 130 kDa membrane glycoprotein. It is a member of the scavenger receptor cysteine-rich superfamily

and is a receptor for the hemoglobin-haptoglobin complex. CD163 is expressed exclusively on the cell surface of

human monocytes and macrophages that evolve predominantly in the late phase of inflammation. CD163 is present

on all CD14 positive monocytes, most CD64 positive monocytes, and shows higher expression on CD16 positive

monocytes. CD163 is upregulated on mononuclear phagocytes by IL-10, IL-6 and dexamethasone.

Lipopolysaccharide (LPS) and phorbol myristate acetate (PMA) both induce shedding of CD163 from the cell surface

into plasma or cell supernatant.

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