货品编号： 博奥森.bs-10440R 品牌：博奥森 品名：富含亮氨酸重复结构域蛋白6抗体 规格：100ul
产品描述：
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs,
such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-
associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also
has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs
are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein
complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]
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