博奥森.bs-17021R KIAA1683蛋白抗体 100ul Bioss


货品编号: 博奥森.bs-17021R 品牌:博奥森 品名:KIAA1683蛋白抗体 规格:100ul

产品描述: KIAA1683 is a 1,180 amino acid protein that contains six IQ domains, exists as three alternatively spliced isoforms, and

is encoded by a gene that maps to human chromosome 19p13.11. Consisting of around 63 million bases with over 1,400

genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting

genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a

number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs,

the CEACAM and PSG families, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19.

Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-

dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be

seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.

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