产品描述： Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat

that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon.

Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic

osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived

growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans,

resulting from unregulated expression of the growth factor.