货品编号： 博奥森.bs-10900r 品牌：博奥森 品名：Rabbit Anti-GAPDH-Loading Control antibody 规格：50ul

产品描述： Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis.

As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also

involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase

activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning

the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age

related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively

expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes

that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36kDa subunits.