货品编号Bioss.bs-10021R

品牌Bioss

品名Anti-NALP3/CIAS1细胞凋亡诱导蛋白NALP3抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:200-800 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量114kDa

细胞定位细胞核 细胞浆 分泌型蛋白

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Cryopyrin:15-120/1036

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as

an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation

of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number

of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.