产品描述： This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific

DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs.

This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by

RefSeq, Jul 2010]

Function: Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other

G/C-rich sequences (By similarity).

Subunit: Interacts with NO66; the interaction is direct and inhibits transcription activator activity.