产品描述： Adipose triglyceride lipase (ATGL) may function as a lipase and play a role in the adaptive response to a low energy state,

such as fasting, by providing fatty acids to other tissues for oxidation. In addition, decreased expression of desnutrin in

obesity models suggests its possible contribution to the pathophysiology of obesity. ATGL catalyzes the initial step in triglyceride

hydrolysis in mammalian adipose tissue. ATGL contains a patatin domain common to plant acyl hydrolases. ATGL is highly

expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with

lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl hydrolase activity. Thus, ATGL and HSL coordinately

catabolize stored triglycerides in adipose tissue of mammals.