货品编号： biovision.K777-100

品牌： biovision

品名： Creatine Kinase (CK) Activity Colorimetric Assay Kit

规格： 100次/盒

产品描述：

Creatine Kinase (CK) also known as creatine phosphokinase (CPK) and ATP: creatine

N-phosphotransferase is a common cellular enzyme (EC 2.7.3.2). It catalyzes the reversible

conversion of creatine and ATP into ADP and phosphocreatine. CK is widely expressed

in various tissues and cell types, with highest activity in striated muscles, heart tissue and

brain. CK consists of two subunits: M (muscle) and B (brain), and has three isoenzymes:

CK-MM (skeleton muscle), CK-MB (cardiac muscle), and CK-BB (brain). Increased CK

level is associated with many diseases such as myocardial infarction, muscular dystrophy,

pulmonary infarction and brain tumors. Accurate measurement of CK is crucial for early

diagnosis, prediction and therapeutic strategy. In BioVision’s Creatine Kinase Activity

Colorimetric Assay kit, creatine kinase converts creatine into phosphocreatine and ADP.

The generated phoshocreatine and ADP reacts with CK Enzyme Mix to form an intermediate

, which reduces a colorless Probe to a colored product with strong absorbance at 450 nm.

The CK Activity Assay is high-throughput adaptable, simple and sensitive. This assay kit can

detect Creatine Kinase activity less than 1 mU.