货品编号: 博奥森.bs-13253R
品牌: 博奥森
品名: G6PASE-β抗体
规格: 100ul
产品描述:
This gene encodes the catalytic subunit of glucose-6-phosphatase (G6Pase). G6Pase is located in the endoplasmic
reticulum (ER) and catalyzes the hydrolysis of glucose-6-phosphate to glucose and phosphate in the last step of the
gluconeogenic and glycogenolytic pathways. Mutations in this gene result in autosomal recessive severe congenital
neutropenia. Multiple transcript variants have been found for this gene, only one of which is expected to express a
protein.[provided by RefSeq, Sep 2009].
Function:
Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate
transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis
and gluconeogenesis. Probably required for normal neutrophil function.
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