货品编号： bioss.bs-2184R

品牌： bioss

品名： Rabbit Anti-NQO1 antibody

规格： 50ul

产品描述：

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This

FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the

one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated

with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of

cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).

Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

Function:

The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in

detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate

residues in prothrombin synthesis.