货品编号： Bioss.bs-0817R
品牌： Bioss
品名： MAGE-1黑色素瘤相关抗原抗体
规格： 100ul
产品描述：
The MAGE 1 gene is a member of the melanoma antigen encoding gene family. These genes encode for HLA-restricted
tumor associated rejection antigens recognized by cytotoxic T lymphocytes. Some of these target antigens may be
potentially useful for cancer specific immunotherapy. The expression of MAGE genes has been reported not only in
melanoma but also in various other malignant tumors such as hepatocellular carcinoma and germ cell tumors.
Function:
May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1.
May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor
transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
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