货品编号： bioss.bs-7792R 品牌：bioss 品名：Rabbit Anti-CLASP1 antibody 规格：100UL/支

产品描述： Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in

the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for

the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell.

May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their

plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is

regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function

at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Function: Microtubule plus-end tracking protein that promotes thestabilization of dynamic microtubules. Involved in the

nucleationof noncentrosomal microtubules originating from the trans-Golginetwork (TGN). Required for the

polarization of the cytoplasmicmicrotubule arrays in migrating cells towards the leading edge ofthe cell. May act

at the cell cortex to enhance the frequency ofrescue of depolymerizing microtubules by attaching their plus-endsto

cortical platforms composed of ERC1 and PHLDB2. This corticalmicrotubule stabilizing activity is regulated at least

in part byphosphatidylinositol 3-kinase signaling. Also performs a similarstabilizing function at the kinetochore which

is essential for thebipolar alignment of chromosomes on the mitotic spindle.