产品描述： Product name Anti-GSDMD antibody [EPR19828] See all GSDMD primary antibodies

Description Rabbit monoclonal [EPR19828] to GSDMD

Host species Rabbit

Specificity In our hands this product works well in western blot using mouse cell lines but not tissue samples. We recommend ab219800 as an alternative

for western blotting of mouse tissue samples.

Tested applications Suitable for: WB, IPmore details

Species reactivity Reacts with: Mouse

Immunogen Synthetic peptide within Mouse GSDMD aa 250-350. The exact sequence is proprietary. Two peptide immunogens within mouse Gasdermin-D

aa 250-350 were used for co-immunisation. Immunogen A mutated at L264E + C265D. Immunogen B mutated at G268D.

Database link: Q9D8T2

Positive control WB: RAW 264.7-derived cell line with ectopic expression of ASC (Apoptosis-associated speck-like protein), untreated and primed with 1 µg/mL

lipopolysaccharides (LPS) for 4 h followed by 10 µM nigericin treatment under serum starved conditions for 2 h, whole cell lysates; J774A.1 IP:

RAW 264.7-derived cells with ectopic expression of ASC, untreated and primed with 1 µg/mL lipopolysaccharides (LPS) for 4 h followed by 10

µM nigericin treatment under serum starved conditions for 2 h, whole cell lysates.