规格：100ul

研究领域 肿瘤细胞生物免疫学发育生物学神经生物学信号转导干细胞细胞骨架 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rat,Chicken,Pig,Cow,Rabbit,Sheep, 产品应用 WB=1:500-2000ELISA=1:500-1000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 53kDa 细胞定位 细胞浆 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from human Vimentin:151-250/466 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed

产品介绍

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin

microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity

of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport

of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a

number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant,

pulverulent cataract.[provided by RefSeq, Jun 2009]

Function: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is

attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.