货品编号: Bioss.bs-23104R 品牌:Bioss 品名:Anti-Ki-67Ki67蛋白抗体
规格:100ul
研究领域 肿瘤细胞生物信号转导转录调节因子细胞类型标志物 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse, 产品应用 ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500Flow-Cyt=1ug/TestICC=1:100-500IF=1:100-500(石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 358kDa 细胞定位 细胞核 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from mouse Ki-67:2701/2800/2938 亚型 IgG 纯化方法 affinity purified by Protein A
储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed
产品介绍
Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and
M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically
quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic
value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong.
Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
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