品牌： Bioss

品名： Anti-P53 protein(wt-p53)肿瘤抑制基因P53蛋白/野生型P53抗体

规格： 100ul

研究领域：肿瘤 细胞生物 染色质和核信号 细胞凋亡 细胞周期蛋白

抗体来源：Rabbit

克隆类型：Polyclonal

交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,

产品应用：WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量：43kDa

细胞定位：细胞核 细胞浆

性 状：Liquid

浓 度：1mg/ml

免 疫 原：KLH conjugated synthetic peptide derived from human P53:251-310/393

亚 型：IgG

纯化方法：affinity purified by Protein A

储 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMed：PubMed

产品介绍：This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding,

and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression

of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism.

Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as

Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple

transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate

translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].