货品编号： Bioss.bs-0052R品牌： Bioss品名： Anti-Caspase 8半胱氨酸蛋白酶8抗体规格：100ul

抗体来源：Rabbit

克隆类型：Polyclonal

交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,

产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量：12/55kDa

细胞定位：细胞浆

性 状：Liquid

浓 度：1mg/ml

免 疫 原：KLH conjugated synthetic peptide derived from rat Caspase-8 subunit p10:411-482/482

亚 型：IgG

纯化方法：affinity purified by Protein A

储 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件：Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMed：PubMed

产品介绍：Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by

proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are

two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation

by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such

as Caspase 8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase

3 and Caspase 7, which in turn cause cell collapse.