品牌： Bioss

品名： Anti-Estrogen receptor beta雌激素受体β 抗体

规格：100ul

研究领域 肿瘤

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat, Pig, Cow,

产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=3μg/Test IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量58kDa

细胞定位细胞核

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human ER-beta:201-300/530

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍This gene encodes a member of the family of estrogenreceptors and superfamily of nuclear receptor

transcriptionfactors. The gene product contains an N-terminal DNA binding domainand C-terminal ligand binding

domain and is localized to thenucleus, cytoplasm, and mitochondria. Upon binding to17beta-estradiol or related

ligands, the encoded protein formshomo- or hetero-dimers that interact with specific DNA sequences toactivate

transcription. Some isoforms dominantly inhibit theactivity of other estrogen receptor family members. Severalalternatively

spliced transcript variants of this gene have beendescribed, but the full-length nature of some of these variants hasnot

been fully characterized. [provided by RefSeq, Jul 2008].