货品编号: Bioss.bs-0164R
品牌: Bioss
品名: Anti-BACE1β分泌酶抗体
规格: 100ul
研究领域神经生物学 信号转导 细胞凋亡 激酶和磷酸酶 合成与降解 Alzheimer's
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit, Guinea Pig,
产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量51kDa
细胞定位细胞浆 细胞膜
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human BACE1:401-501/501
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease.
Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein(APP) by two proteases,
one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein
family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple
transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq].
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