货品编号: Bioss.bs-0217R-100ul
品牌: Bioss
品名: Anti-bFGF碱性成纤维细胞生长因子/FGF2抗体
规格: 100ul
研究领域肿瘤 心血管 细胞生物 免疫学 生长因子和激素 细胞因子
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Cow, Rabbit, Sheep,
产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量18kDa
细胞定位细胞核 分泌型蛋白
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human bFGF:143-250/288
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family
members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated
in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth.
The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG)
and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are
localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic
and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008].
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