货品编号: Bioss.bs-0216R-100ul
品牌: Bioss
品名: Anti-Fas LigandFasL抗体
规格: 100ul
研究领域肿瘤 细胞生物 免疫学 细胞凋亡
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Cow,
产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量31kDa
细胞定位细胞核 细胞膜 细胞外基质 分泌型蛋白
性 状Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Fas Ligand:196-281/281
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍FasL (CD95L) is a cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic
signal into cells. May be involved in cytotoxic T cell mediated apoptosis and in T cell development.
TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the
antigen-stimulated suicide of mature T cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3
modulates its effects. Homotrimer (Probable). May be released as type II membrane protein. Belongs to
the tumor necrosis factor family
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