货品编号Bioss.bs-0533R

品牌Bioss

品名Anti-GABABR1gamma氨基丁酸B型受体1抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Cow, Horse,

产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量108kDa

细胞定位细胞浆 细胞膜 分泌型蛋白

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human GABABR1:

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian

central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to

produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow,

prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related

7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B)

receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the

HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been

mapped in this region. Alternative splicing of this gene generates multiple transcript variants.