货品编号： Bioss.bs-4615R 品 牌： Bioss 品 名： Anti-ICAM1细胞间粘附分子1抗体 规 格： 100ul 研究领域 肿瘤免疫学信号转导干细胞细胞粘附分子细胞表面分子糖蛋白t-淋巴细胞b-淋巴细胞 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rabbit, 产品应用 WB=1:500-2000ELISA=1:500-1000Flow-Cyt=1μg/Test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 56kDa 细胞定位 细胞膜 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from human CD54/ICAM-1:451-505/532<Cytoplasmic> 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed

产品介绍 This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system.

It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by

RefSeq, Jul 2008].

Function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial

migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.

In case of rhinovirus infection acts as a cellular receptor for the virus.