货品编号： Bioss.bs-5559R 品 牌： Bioss 品 名：Anti-phospho-PKC delta (Ser645)磷酸化蛋白激酶C亚性D型抗体 规 格： 100ul 产品类型 磷酸化抗体 研究领域 肿瘤细胞生物免疫学信号转导转录调节因子激酶和磷酸酶 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rat, 产品应用 ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500Flow-Cyt=1:100-500IF=1:100-500（石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 77kDa 细胞定位 细胞核细胞浆细胞膜 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated Synthesised phosphopeptide derived from human PKC delta around the phosphorylation site of Ser645:RL(p-S)YS 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed

产品介绍 Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second

messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse

cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each

member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene

is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the

regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same

protein have been observed. [provided by RefSeq, Jul 2008].