货品编号： Bioss.bs-5628R 品 牌： Bioss 品 名：Anti-phospho-Alpha synuclein (Ser129)磷酸化核突触蛋白α抗体 规 格： 100ul 产品类型 磷酸化抗体 研究领域 免疫学神经生物学信号转导细胞凋亡转录调节因子细胞骨架 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep, 产品应用 WB=1:500-2000ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500Flow-Cyt=1ug/TestIF=1:100-500（石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 15kDa 细胞定位 细胞核细胞浆细胞膜 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated Synthesised phosphopeptide derived from human SNCA around the phosphorylation site of Ser129:MP(p-S)EE 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. PubMed PubMed

产品介绍 Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed

in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane

trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques

in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

[provided by RefSeq, Feb 2016]..