货品编号Bioss.bs-0905R

品牌Bioss

品名Anti-p53 (Acetyl K382)乙酰化P53(Lys382)抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Dog,

产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量43kDa

细胞定位细胞核 细胞浆

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated Synthesised acetylpeptide derived from human p53 around the acetylation site of K382:HK(Ac-K)LM

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and

oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate

expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or

changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including

hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate

promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to

result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).