货品编号Bioss.bs-1014R

品牌Bioss

品名Anti-CD11b整合素αM/巨噬细胞表面分子抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Pig,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量125kDa

细胞定位细胞膜

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human CD11b:77-180

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed

of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2)

to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b)

receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to

stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants

encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]