货品编号Bioss.bs-10274R

品牌Bioss

品名Anti-IL-2白介素2抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

细胞定位细胞浆

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human IL-2:31-130/153

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The

receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin

4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents

an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a

similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the

immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is

probably mediated by cytotoxic effector cells.