Bioss.bs-10614R Anti-TNNI3 心肌肌钙蛋白I抗体 100ulBioss


货品编号Bioss.bs-10614R

品牌Bioss

品名Anti-TNNI3心肌肌钙蛋白I抗体

规格100ul

研究领域心血管 发育生物学 信号转导 干细胞 细胞骨架

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量24kDa

细胞定位细胞浆

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human TNNI3:131-210/210

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin

complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions

and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch,

TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed

in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and

familial restrictive cardiomyopathy (RCM). [provided by RefSeq].

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