货品编号Bioss.bs-1060R

品牌Bioss

品名Anti-Cytokeratin 5细胞角蛋白5抗体

规格100ul

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,

产品应用WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量64kDa

细胞定位细胞核 细胞浆 细胞外基质

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human CK5:331-430/590

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinising tissue (ie., skin) and non

keratinising cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins

have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the

molecular range of 40 to 70 kDa and isoelectric points of 5 to 8.5 can be identified using two dimensional gel

electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides)

and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is

expressed in all epithelial cells. Defects in KRT5 are a cause of epidermolysis bullosa simplex.