货品编号： Bioss.bs-6959R 品 牌： Bioss 品 名：Anti-phospho-Estrogen Receptor beta (Ser87)磷酸化雌激素受体β抗体 规 格： 100ul 研究领域 肿瘤细胞生物免疫学染色质和核信号信号转导转录调节因子 抗体来源 Rabbit 克隆类型 Polyclonal 交叉反应 Human,Mouse,Rat,Rabbit,Sheep, 产品应用 WB=1:500-2000ELISA=1:500-1000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 66kDa 细胞定位 细胞核 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthesised phosphopeptide derived from human Estrogen Receptor beta around the phosphorylation site of Ser87:HL(p-S)PL 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMed PubMed

产品介绍 Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen

receptors, including ER alpha and ER beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal

function of reproductive tissues. ER alpha and ER beta A have been shown to be differentially activated by various ligands. Receptor-ligand

interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association

of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER alpha and ER beta may be regulated

by distinct mechanisms even though they share many functional characteristics.