货品编号： Bioss.bsm-2346M 品 牌： Bioss 品 名：Anti-P53(wt-p53) (D2F7)肿瘤抑制基因野生型P53单抗100ul 规 格： 100ul 研究领域 肿瘤细胞生物免疫学细胞凋亡 抗体来源 Mouse 克隆类型 Monoclonal 克隆号 D2F7 交叉反应 Human,Mouse,Rat, 产品应用 WB=1:500-2000ELISA=1:500-1000IF=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 43kDa 细胞定位 细胞核细胞浆 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthetic peptide derived from human P53(wt-p53):341-393/393 亚型 IgG 纯化方法 affinity purified by Protein A 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMed PubMed

产品介绍 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains.

The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest,

apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers,

including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result

in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation

initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].