货品编号Bioss.bs-1646R

品牌Bioss

品名Anti-phospho-ERK1 (Thr202/Tyr204) + ERK2 (Thr183/Tyr185)磷酸化丝裂原活化蛋白激酶1/2抗体

规格100ul

产品类型磷酸化抗体

研究领域神经生物学 信号转导 干细胞 激酶和磷酸酶

抗体来源Rabbit

克隆类型Polyclonal

交叉反应Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Guinea Pig,

产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg /test IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量41kDa

细胞定位细胞核 细胞浆

性 状Liquid

浓 度1mg/ml

免 疫 原KLH conjugated Synthesised phosphopeptide derived from mouse ERK1/2 around the phosphorylation site of Thr202/Tyr204:FL(p-T)E(p-Y)VA

亚 型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

PubMedPubMed

产品介绍The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular

signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide

variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation

of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus

of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the

same protein, but differing in the UTRs, have been reported for this gene.