货品编号： Bioss.bsm-33209M 品 牌： Bioss 品 名：Anti-P53(Mono Methyl Lys370)甲基化P53(Mono Methyl Lys370)单克隆抗体 规 格： 100ul 产品类型 甲基化抗体 研究领域 肿瘤细胞生物神经生物学信号转导细胞凋亡 抗体来源 Mouse 克隆类型 Monoclonal 克隆号 5B10 交叉反应 Human,Mouse,Rat, 产品应用 WB=1:500-2000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分子量 53kDa 细胞定位 细胞核细胞浆 性状 Liquid 浓度 1mg/ml 免疫原 KLH conjugated synthesised methylpeptide derived from human P53 around the methylation site of Mono Methyl Lys370:HL(Mono Methyl K)SK 亚型 IgG 纯化方法 affinity purified by Protein G 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

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产品介绍 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein

responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or

changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni

syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have

also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].